Anti-CBX2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA023083.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA023083.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex... more

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Product information "Anti-CBX2"

Protein function: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development (PubMed:21282530). PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (PubMed:21282530). Binds to histone H3 trimethylated at 'Lys-9' (H3K9me3) or at 'Lys-27' (H3K27me3). Plays a role in the lineage differentiation of the germ layers in embryonic development. Involved in sexual development, acting as activator of NR5A1 expression (PubMed:19361780). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 77% and to rat: 76%

Keywords:	Anti-CBX2, Anti-Chromobox protein homolog 2
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA023083

Properties

Application:	ICC, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: KRDCVKGSAT PSGQESRTAP GEARKAATLP EMSAGEESSS SDSDPDSASP PSTGQNPSVS VQTSQDWKPT RSLIEHVFVT DVTANLITVT VKESPTSV (ATA-APrEST75821)