Anti-CAR16

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ELK-ES17860.50	50 µl		-	-	Request delivery time estimate		169.00€
ELK-ES17860.100	100 µl		-	-	Request delivery time estimate		283.00€

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Protein function: Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation... more

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Product information "Anti-CAR16"

Protein function: Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF- alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000. Cellular localization:

Keywords:	Anti-COP, Anti-CARD16, Anti-Pseudo-ICE, Anti-CARD-only protein 1, Anti-Caspase-1 inhibitor COP, Anti-Pseudo-IL1B-converting enzyme, Anti-Caspase recruitment domain-only protein 1, Anti-Pseudo interleukin-1 beta converting enzyme, CAR16 rabbit pAb
Supplier:	ELK Biotechnology
Supplier-Nr:	ES17860

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, rat, mouse,
Immunogen:	Synthesized peptide derived from human CAR16 AA range: 101-151
Format:	Purified

Database Information

KEGG ID :	K12806 \| Matching products
UniProt ID :	Q5EG05 \| Matching products
Gene ID	GeneID 114769 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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