Anti-Capillary Morphogenesis Gene 2 (CMG-2, Anthrax Toxin Receptor 2, ANTXR2)

CMG-2, also known as anthrax toxin receptor 2 (ANTXR2) is a 45kD type I membrane protein with a von Willebrand factor A/integrin-like inserted domain in its extracellular region. CMG-2 binds laminin and collagen type IV. It also interacts with the protective antigen (PA) subunit of anthrax toxin. Applications: Suitable for use in ELISA and Western Blot. , Other applications not tested. Recommended Dilution: Western Blot: 0.1-0.2ug/ml. The detection limit for rmCMG-2 is approximately 5ng/lane under non-reducing and reducing conditions. , ELISA: 0.5-1ug/ml. The detection limit for rmCMG-2 is approximately 1.5ng/well. , Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol, PBS. Aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.