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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-35-1609-50 | 50 µl | - |
3 - 11 business days* |
574.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in... more
Product information "Anti-CaMKII (Ab-286)"
CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity Protein function: Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in synaptic plasticity, neurotransmitter release and long-term potentiation. Member of the NMDAR signaling complex in excitatory synapses, it regulates NMDAR-dependent potentiation of the AMPAR and therefore excitatory synaptic transmission. Regulates dendritic spine development (PubMed:28130356). Also regulates the migration of developing neurons (PubMed:29100089). Phosphorylates the transcription factor FOXO3 to activate its transcriptional activity (PubMed:23805378). Acts as a negative regulator of 2- arachidonoylglycerol (2-AG)-mediated synaptic signaling via modulation of DAGLA activity. [The UniProt Consortium]
Keywords: | Anti-CAMKA, Anti-CAMK2A, Anti-CaMK-II subunit alpha, Anti-CaM kinase II subunit alpha, Anti-Calcium/calmodulin-dependent protein kinase type II subunit alpha, Polyclonal Antibody to CaMKII (Ab-286) |
Supplier: | Abeomics |
Supplier-Nr: | 35-1609-50 |
Properties
Application: | WB, IF |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Peptide sequence around aa.284~288 (Q-E-T-V-D) derived from Human CaMKII. |
Format: | Purified |
Database Information
KEGG ID : | K04515 | Matching products |
UniProt ID : | Q9UQM7 | Matching products |
Gene ID | GeneID 815 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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