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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-EA214.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Calnexin is a chaperone, characterized by assisting protein folding and quality control, ensuring... more
Product information "Anti-Calnexin"
Calnexin is a chaperone, characterized by assisting protein folding and quality control, ensuring that only properly folded and assembled proteins proceed further along the secretory pathway. Calnexin is a integral protein (that appears variously as a 90kDa, 80kDa or 75kDa band on western blotting depending on the source of the antibody) of the endoplasmic reticulum (ER). It consists of a large (50 kDa) N-terminal calcium-binding lumenal domain, a single transmembrane helix and a short (90 residues), acidic cytoplasmic tail. Protein function: Calcium-binding protein that interacts with newly synthesized monoglucosylated glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse. [The UniProt Consortium] Recommended dilutions: WB 1:1,000-2,000 IHC 1:200-500. Cellular localization: Endoplasmic reticulum membrane,Melanosome.
Keywords: | Anti-p90, Anti-IP90, Anti-CANX, Anti-Calnexin, Anti-Major histocompatibility complex class I antigen-binding protein p88, Calnexin Rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | EA214 |
Properties
Application: | WB, IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Recombinant Protein |
MW: | 75,80,90 kD |
Format: | Purified |
Database Information
KEGG ID : | K08054 | Matching products |
UniProt ID : | P27824 | Matching products |
Gene ID | GeneID 821 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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