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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-F54641-0.08ML | 80 µl | - | - |
3 - 10 business days* |
326.00€
|
||
NSJ-F54641-0.4ML | 400 µl | - | - |
3 - 10 business days* |
702.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
In 1X PBS, pH 7.4, with 0.09% sodium azide. The protein encoded by this gene is a brain-enriched... more
Product information "Anti-CalDAG-GEFI / RASGRP2"
In 1X PBS, pH 7.4, with 0.09% sodium azide. The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene. Protein function: Functions as a calcium- and DAG-regulated nucleotide exchange factor specifically activating Rap through the exchange of bound GDP for GTP. May also activates other GTPases such as RRAS, RRAS2, NRAS, KRAS but not HRAS. Functions in aggregation of platelets and adhesion of T-lymphocytes and neutrophils probably through inside-out integrin activation. May function in the muscarinic acetylcholine receptor M1/CHRM1 signaling pathway. [The UniProt Consortium]
Keywords: | Anti-CDC25L, Anti-RASGRP2, Anti-hCDC25L, Anti-CalDAG-GEFI, Anti-Cdc25-like protein, Anti-F25B3.3 kinase-like protein, Anti-RAS guanyl-releasing protein 2, Anti-Calcium and DAG-regulated guanine nucleotide exchange factor I, CalDAG-GEFI Antibody / RASGRP2 |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | F54641 |
Properties
Application: | IF, IHC (paraffin), WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | A portion of amino acids 7-34 from the human protein |
Format: | Purified |
Database Information
KEGG ID : | K12361 | Matching products |
UniProt ID : | Q7LDG7 | Matching products |
Gene ID | GeneID 10235 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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You will get a certificate here
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