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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES7657.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES7657.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto... more
Product information "Anti-CAF-1 p60"
Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair. [provided by RefSeq, Jul 2008], Protein function: Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA, histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.. Cellular localization: Nucleus . Cytoplasm . DNA replication foci. Cytoplasmic in M phase.
Keywords: | Anti-CAF1A, Anti-CAF-I p60, Anti-CAF-1 subunit B, Anti-CAF-I 60 kDa subunit, Anti-M-phase phosphoprotein 7, Anti-Chromatin assembly factor 1 subunit B, Anti-Chromatin assembly factor I p60 subunit, CAF-1 p60 rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES7657 |
Properties
Application: | WB, IHC, IF, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | The antiserum was produced against synthesized peptide derived from human CAF1B. AA range:71-120 |
MW: | 61 kD |
Format: | Antiserum |
Database Information
KEGG ID : | K10751 | Matching products |
UniProt ID : | Q13112 | Matching products |
Gene ID | GeneID 8208 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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