Anti-CAF-1 p150

Anti-CAF-1 p150
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES4412.50 50 µl - -

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169.00€
ELK-ES4412.100 100 µl - -

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283.00€
 
Chromatin assembly factor I (CAF1) is a nuclear complex consisting of p50, p60 (CHAF1B, MIM... more
Product information "Anti-CAF-1 p150"
Chromatin assembly factor I (CAF1) is a nuclear complex consisting of p50, p60 (CHAF1B, MIM 601245), and p150 (CHAF1A) subunits that assembles histone octamers onto replicating DNA in vitro (Kaufman et al., 1995 [PubMed 7600578]).[supplied by OMIM, Mar 2008], Protein function: Core component of the CAF-1 complex, a complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA, histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci. [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.. Cellular localization: Nucleus . DNA replication foci.
Keywords: Anti-CAF, Anti-hp150, Anti-CAF-I p150, Anti-CAF-1 subunit A, Anti-CAF-I 150 kDa subunit, Anti-Chromatin assembly factor 1 subunit A, Anti-Chromatin assembly factor I p150 subunit, CAF-1 p150 rabbit pAb
Supplier: ELK Biotechnology
Supplier-Nr: ES4412

Properties

Application: WB, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: Synthesized peptide derived from CAF-1 p150 . at AA range: 300-380
MW: 150 kD
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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