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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES2068.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES2068.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
microtubule affinity regulating kinase 3(MARK3) Homo sapiens The protein encoded by this gene is... more
Product information "Anti-C-TAK1"
microtubule affinity regulating kinase 3(MARK3) Homo sapiens The protein encoded by this gene is activated by phosphorylation and in turn is involved in the phosphorylation of tau proteins MAP2 and MAP4. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011], Protein function: Serine/threonine-protein kinase (PubMed:16822840, PubMed:16980613, PubMed:23666762). Involved in the specific phosphorylation of microtubule-associated proteins for MAP2 and MAP4. Phosphorylates the microtubule-associated protein MAPT/TAU (PubMed:23666762). Phosphorylates CDC25C on 'Ser-216' (PubMed:12941695). Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus (PubMed:16980613). Regulates localization and activity of MITF by mediating its phosphorylation, promoting subsequent interaction between MITF and 14-3-3 and retention in the cytosol (PubMed:16822840). Negatively regulates the Hippo signaling pathway and antagonizes the phosphorylation of LATS1. Cooperates with DLG5 to inhibit the kinase activity of STK3/MST2 toward LATS1 (PubMed:28087714). Phosphorylates PKP2 and KSR1 (PubMed:12941695). [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.. Cellular localization: Cell membrane , Peripheral membrane protein . Cell projection, dendrite . Cytoplasm .
Keywords: | Anti-EMK-2, Anti-MARK3, Anti-CTAK1, Anti-cTAK1, Anti-C-TAK1, Anti-Par-1a, Anti-ELKL motif kinase 2, Anti-Protein kinase STK10, Anti-Ser/Thr protein kinase PAR-1, Anti-Cdc25C-associated protein kinase 1, Anti-Serine/threonine-protein kinase p78, C-TAK1 rab |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES2068 |
Properties
Application: | WB, IHC, IF, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | The antiserum was produced against synthesized peptide derived from human MARK3. AA range:1-50 |
MW: | 85 kD |
Format: | Antiserum |
Database Information
KEGG ID : | K08798 | Matching products |
UniProt ID : | P27448 | Matching products |
Gene ID | GeneID 4140 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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