Anti-c-Myc, clone MYC275

Anti-c-Myc, clone MYC275
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3158IHC-7ML 7 ml - -

3 - 10 business days

541.00€
 
Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*. The... more
Product information "Anti-c-Myc, clone MYC275"
Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*. The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment. Protein function: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'- CAC[GA]TG-3'. Activates the transcription of growth-related genes. [The UniProt Consortium]
Keywords: Anti-MYC, Anti-BHLHE39, Anti-bHLHe39, Anti-Proto-oncogene c-Myc, Anti-Transcription factor p64, Anti-Myc proto-oncogene protein, Anti-Class E basic helix-loop-helix protein 39, c-Myc Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V3158IHC-7ML

Properties

Application: IHC
Antibody Type: Monoclonal
Clone: MYC275
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Recombinant human protein was used as the immunogen for this c-Myc antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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