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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-EA329.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
c-Jun is a member of the Jun Family containing c-Jun, JunB and JunD, and is a component of the... more
Product information "Anti-c-Jun"
c-Jun is a member of the Jun Family containing c-Jun, JunB and JunD, and is a component of the transcription factor AP-1 (activator protein-1). Protein function: Transcription factor that recognizes and binds to the AP-1 consensus motif 5'-TGA[GC]TCA-3' (PubMed:10995748, PubMed:22083952). Heterodimerizes with proteins of the FOS family to form an AP-1 transcription complex, thereby enhancing its DNA binding activity to the AP-1 consensus sequence 5'-TGA[GC]TCA-3' and enhancing its transcriptional activity. Together with FOSB, plays a role in activation-induced cell death of T cells by binding to the AP-1 promoter site of FASLG/CD95L, and inducing its transcription in response to activation of the TCR/CD3 signaling pathway (PubMed:12618758). Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation (PubMed:17210646). Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306). [The UniProt Consortium] Recommended dilutions: WB 1:1,000-2,000 IHC 1:100-200. Cellular localization: Nucleus
Keywords: | Anti-p39, Anti-AP1, Anti-JUN, Anti-Activator protein 1, Anti-Proto-oncogene c-Jun, Anti-Transcription factor Jun, Anti-Transcription factor AP-1 subunit Jun, Anti-V-jun avian sarcoma virus 17 oncogene homolog, c-Jun Rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | EA329 |
Properties
Application: | WB, IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Recombinant Protein |
MW: | 43 kD |
Format: | Purified |
Database Information
KEGG ID : | K04448 | Matching products |
UniProt ID : | P05412 | Matching products |
Gene ID | GeneID 3725 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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