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![Anti-Bst2](https://www.biomol.com/media/image/ca/b4/d8/600-401-Z95_600x600.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
600-401-Z95 | 100 µg | - | - |
6 - 10 business days* |
684.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Anti-Bst2 Antibody was affinity purified from monospecific antiserum by immunoaffinity... more
Product information "Anti-Bst2"
Anti-Bst2 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Bst2 from other sources has not been determined. Protein function: IFN-induced antiviral host restriction factor which efficiently blocks the release of diverse mammalian enveloped viruses by directly tethering nascent virions to the membranes of infected cells. Acts as a direct physical tether, holding virions to the cell membrane and linking virions to each other. The tethered virions can be internalized by endocytosis and subsequently degraded or they can remain on the cell surface. In either case, their spread as cell-free virions is restricted. Its target viruses belong to diverse families, including retroviridae: human immunodeficiency virus type 1 (HIV-1), mouse mammary tumor virus (MMTV) and murine leukemia virus (MLV), filoviridae: ebola virus (EBOV), arenaviridae: lassa virus (LASV), and rhabdoviridae: vesicular stomatitis virus (VSV). Can inhibit cell surface proteolytic activity of MMP14 causing decreased activation of MMP15 which results in inhibition of cell growth and migration. Can stimulate signaling by LILRA4/ILT7 and consequently provide negative feedback to the production of IFN by plasmacytoid dendritic cells in response to viral infection. Plays a role in the organization of the subapical actin cytoskeleton in polarized epithelial cells. [The UniProt Consortium]
Keywords: | Anti-Bst2, Anti-CD317, Anti-BST-2, Anti-HM1.24 antigen, Anti-Bone marrow stromal antigen 2 |
Supplier: | Rockland Immunochemicals |
Supplier-Nr: | 600-401-Z95 |
Properties
Application: | ELISA, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse |
Immunogen: | 18 amino acid synthetic peptide near the N-terminus of the mouse Bst2. |
Format: | Purified |
Database Information
KEGG ID : | K06731 | Matching products |
UniProt ID : | Q8R2Q8 | Matching products |
Gene ID | GeneID 69550 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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