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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ARG59380.50 | 50 µl | - | - |
6 - 14 business days* |
520.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Acts both as coactivator and as corepressor. May play a role in chromatin... more
Product information "Anti-BRD7"
Protein function: Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. Induces dephosphorylation of GSK3B at 'Tyr-216'. Down-regulates TRIM24-mediated activation of transcriptional activation by AR. Transcriptional corepressor that down-regulates the expression of target genes. Binds to target promoters, leading to increased histone H3 acetylation at 'Lys-9' (H3K9ac). Binds to the ESR1 promoter. Recruits BRCA1 and POU2F1 to the ESR1 promoter. Coactivator for TP53-mediated activation of transcription of a set of target genes. Required for TP53-mediated cell-cycle arrest in response to oncogene activation. Promotes acetylation of TP53 at 'Lys-382', and thereby promotes efficient recruitment of TP53 to target promoters. Inhibits cell cycle progression from G1 to S phase. [The UniProt Consortium]
| Keywords: | Anti-BRD7, Anti-BP75, Anti-Protein CELTIX-1, Anti-Protein CELTIX-1, Anti-75 kDa bromodomain protein, Anti-75 kDa bromodomain protein, Anti-Bromodomain-containing protein 7, Anti-Bromodomain-containing protein 7 |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG59380 |
Properties
| Application: | WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human |
| Immunogen: | Recombinant fusion protein corresponding to aa. 1-95 of Human BRD7 (NP_037395.2) |
| MW: | 74 kD |
| Format: | Affinity Purified |
Database Information
| KEGG ID : | K11723 | Matching products |
| UniProt ID : | Q9NPI1 | Matching products |
| Gene ID | GeneID 29117 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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