Anti-BPIFA1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
G-CAB8634.20	20 µl		-		9 - 20 business days*		149.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Lipid-binding protein which shows high specificity for the surfactant... more

Close menu

Product information "Anti-BPIFA1"

Protein function: Lipid-binding protein which shows high specificity for the surfactant phospholipid dipalmitoylphosphatidylcholine (DPPC) (PubMed:25223608). Plays a role in the innate immune responses of the upper airways (PubMed:23499554, PubMed:23132494). Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P.aeruginosa and K.pneumoniae (PubMed:23499554, PubMed:23132494, PubMed:27145151). Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid homeostasis and proper clearance of mucus (PubMed:24124190, PubMed:24043776). Plays a role in the airway inflammatory response after exposure to irritants (PubMed:11425234). May attract macrophages and neutrophils (PubMed:23132494). [The UniProt Consortium]

Keywords:	Anti-LUNX, Anti-BPIFA1, Anti-SPLUNC1, Anti-Short PLUNC1, Anti-Von Ebner protein Hl, Anti-Lung-specific protein X, Anti-Tracheal epithelium-enriched protein, Anti-BPI fold-containing family A member 1, Anti-Nasopharyngeal carcinoma-related protein
Supplier:	Assay Genie
Supplier-Nr:	CAB8634

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	mouse, rat
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 20-256 of human BPIFA1 (NP_057667.1).