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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-EA263.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Bombesin receptor 2 (BB2) is a member of a family of receptors that binds the 14 amino acid... more
Product information "Anti-Bombesin Receptor 2"
Bombesin receptor 2 (BB2) is a member of a family of receptors that binds the 14 amino acid peptide, bombesin. Protein function: Receptor for gastrin-releasing peptide (GRP) (PubMed:1655761). Signals via association with G proteins that activate a phosphatidylinositol-calcium second messenger system, resulting in Akt phosphorylation. Contributes to the regulation of food intake. Contributes to the perception of prurient stimuli and transmission of itch signals in the spinal cord that promote scratching behavior, but does not play a role in the perception of pain. Contributes primarily to nonhistaminergic itch sensation. In one study, shown to act in the amygdala as part of an inhibitory network which inhibits memory specifically related to learned fear. In another study, shown to contribute to disinhibition of glutamatergic cells in the auditory cortex via signaling on vasoactive intestinal peptide- expressing cells which leads to enhanced auditory fear memories. Contributes to the induction of sighing through signaling in the pre-Botzinger complex, a cluster of several thousand neurons in the ventrolateral medulla responsible for inspiration during respiratory activity. [The UniProt Consortium] Recommended dilutions: WB 1:1,000-2,000 IHC 1:100-200. Cellular localization: Cell membrane
Keywords: | Anti-GRPR, Anti-GRP-R, Anti-GRP-preferring bombesin receptor, Anti-Gastrin-releasing peptide receptor, Bombesin Receptor 2 Rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | EA263 |
Properties
Application: | WB, IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Synthetic Peptide |
MW: | 50-70 kD |
Format: | Purified |
Database Information
KEGG ID : | K04169 | Matching products |
UniProt ID : | P30550 | Matching products |
Gene ID | GeneID 2925 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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