Anti-Biotinylated Mouse Monoclonal Antibody to Human C-reactive protein (Clone: 8B11)

C-reactive protein (CRP) is an annular, pentameric protein found in blood plasma, in which the levels rise in response to inflammation. It is an acute-phase protein synthesized by the liver that increases following interleukin-6 secretion by macrophages and T cells. CRP binds to the phosphocholine expressed on the surface of dead or dying cells and some bacteria. This activates the complement system, promoting phagocytosis by macrophages, which clears necrotic and apoptotic cells and bacteria.