Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ARG54094.100 | 100 µl | - | - |
6 - 14 business days* |
624.00€
|
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Protein function: Plays a central role in autophagy (PubMed:23184933). Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate, different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3- C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123, PubMed:20208530). Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex forms. Involved in endocytosis (PubMed:25275521). Protects against infection by a neurovirulent strain of Sindbis virus (PubMed:9765397). May play a role in antiviral host defense. [The UniProt Consortium]
Keywords: | Anti-BECN1, Anti-GT197 |
Supplier: | Arigo Biolaboratories |
Supplier-Nr: | ARG54094 |
Properties
Application: | WB |
Antibody Type: | Monoclonal |
Clone: | 4F4-B10-C9 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human, mouse, rat, monkey, hamster |
Immunogen: | Purified recombinant human Beclin 1 protein fragments expressed in E.coli |
Format: | Affinity Purified |
Database Information
KEGG ID : | K08334 | Matching products |
UniProt ID : | Q14457 | Matching products |
Gene ID | GeneID 8678 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Our products are for laboratory research use only: Not for administration to humans!