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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V2305-20UG | 20 µg | - | - |
3 - 10 business days* |
332.00€
|
||
NSJ-V2305-100UG | 100 µg | - | - |
3 - 10 business days* |
752.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Bcl10, with an N-terminal caspase... more
Product information "Anti-Bcl10, clone BL10/411"
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Bcl10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1,14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of Bcl10 was shown to induce NF?B activation in a NIK-dependent pathway. This antibody labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas. In MALT lymphomas with the t(1,14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level. Protein function: Involved in adaptive immune response (PubMed:25365219). Promotes apoptosis, pro-caspase-9 maturation and activation of NF- kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1 (PubMed:18264101). [The UniProt Consortium]
Keywords: | Anti-mE10, Anti-CIPER, Anti-c-E10, Anti-BCL10, Anti-hCLAP, Anti-Bcl-10, Anti-cCARMEN, Anti-Cellular-E10, Anti-B-cell CLL/lymphoma 10, Anti-Cellular homolog of vCARMEN, Anti-B-cell lymphoma/leukemia 10, Anti-CARD-like apoptotic protein, Bcl10 Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V2305 |
Properties
Application: | WB, FC, IHC, IF |
Antibody Type: | Monoclonal |
Clone: | BL10/411 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Human Bcl10 recombinant protein (epitope aa 122-168) was used as the immunogen for this antibody. |
Format: | Purified |
Database Information
KEGG ID : | K07368 | Matching products |
UniProt ID : | O95999 | Matching products |
Gene ID | GeneID 8915 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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