Anti-Bax (BCL2-associated X protein, Apoptosis regulator BAX, cytoplasmic isoform beta, Apoptosis re

Bax belongs to Bcl-2 protein family and accelerates the apoptosis by binding to the repressor Bcl-2. It can form oligomers and targets mitochondrial membrane inducing an increase in the membrane permeability which leads to the release of cytochrome c from mitochondria and the activation of the caspase pathway. Bax is considered a tumor suppressor. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.