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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ARG10281.200 | 200 µg | - | - |
6 - 14 business days* |
624.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: One of the three proteins composing the anthrax toxin, the agent which infects... more
Product information "Anti-Bacillus anthracis lethal factor, clone BAL0105"
Protein function: One of the three proteins composing the anthrax toxin, the agent which infects many mammalian species and that may cause death. LF is the lethal factor that, when associated with PA, causes death. LF is not toxic by itself. It is a protease that cleaves the N-terminal of most dual specificity mitogen-activated protein kinase kinases (MAPKKs or MAP2Ks) (except for MAP2K5). Cleavage invariably occurs within the N-terminal proline-rich region preceding the kinase domain, thus disrupting a sequence involved in directing specific protein-protein interactions necessary for the assembly of signaling complexes. There may be other cytosolic targets of LF involved in cytotoxicity. The proteasome may mediate a toxic process initiated by LF in the cell cytosol involving degradation of unidentified molecules that are essential for macrophage homeostasis. This is an early step in LeTx intoxication, but it is downstream of the cleavage by LF of MEK1 or other putative substrates. [The UniProt Consortium]
Keywords: | Anti-LF, Anti-lef, Anti-pXO1-107, EC=3.4.24.83, Anti-Lethal factor, Anti-Anthrax lethal toxin endopeptidase component |
Supplier: | Arigo Biolaboratories |
Supplier-Nr: | ARG10281 |
Properties
Application: | ELISA |
Antibody Type: | Monoclonal |
Clone: | BAL0105 |
Conjugate: | No |
Host: | Mouse |
Immunogen: | Highly purified lethal factor antigen of Bacillus anthracis |
Format: | Purified |
Database Information
KEGG ID : | K08645 | Matching products |
UniProt ID : | P15917 | Matching products |
Gene ID | GeneID 2820148 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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