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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A4156-65E.50 | 50 µg | - | - |
3 - 19 business days* |
796.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the... more
Product information "Anti-ATRX, CT (Transcriptional Regulator ATRX, ATP-dependent Helicase ATRX, X-linked Helicase II, X-"
The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. The mutations of this gene are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry (FFPE): 5ug/ml. Requires HIER using sodium citrate buffer, pH 6.0., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | Anti-XNP, Anti-ATRX, Anti-RAD54L, Anti-Znf-HX, EC=3.6.4.12, Anti-X-linked helicase II, Anti-X-linked nuclear protein, Anti-ATP-dependent helicase ATRX, Anti-Transcriptional regulator ATRX |
Supplier: | United States Biological |
Supplier-Nr: | A4156-65E |
Properties
Application: | ELISA, IHC, WB |
Antibody Type: | Monoclonal |
Clone: | 60.1 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Synthetic peptide corresponding to human ATRX at C-terminal (KLH). |
Format: | Affinity Purified |
Database Information
KEGG ID : | K10779 | Matching products |
UniProt ID : | P46100 | Matching products |
Gene ID | GeneID 546 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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