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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ARG65744.50 | 50 µg | - | - |
6 - 14 business days* |
536.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Catalyzes the hydrolysis of ATP coupled with the transport of calcium from the... more
Product information "Anti-ATP2B1 / PMCA1"
Protein function: Catalyzes the hydrolysis of ATP coupled with the transport of calcium from the cytoplasm to the extracellular space thereby maintaining intracellular calcium homeostasis. Plays a role in blood pressure regulation through regulation of intracellular calcium concentration and nitric oxide production leading to regulation of vascular smooth muscle cells vasoconstriction. Positively regulates bone mineralization through absorption of calcium from the intestine. Plays dual roles in osteoclast differentiation and survival by regulating RANKL-induced calcium oscillations in preosteoclasts and mediating calcium extrusion in mature osteoclasts. Regulates insulin sensitivity through calcium/calmodulin signaling pathway by regulating AKT1 activation and NOS3 activation in endothelial cells (PubMed:29104511). [The UniProt Consortium]
| Keywords: | Anti-PMCA1, Anti-Plasma membrane calcium pump isoform 1, Anti-Plasma membrane calcium ATPase isoform 1, Anti-Plasma membrane calcium-transporting ATPase 1 |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG65744 |
Properties
| Application: | WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Goat |
| Species reactivity: | human (Expected: mouse, rat, cow, dog, swine) |
| Immunogen: | Synthetic peptide around the internal region of Human ATP2B1. (C-KQDGAIENRNKAKAQD) |
| MW: | 135 kD |
| Format: | Antigen Affinity Purified |
Database Information
| KEGG ID : | K05850 | Matching products |
| UniProt ID : | P20020 | Matching products |
| Gene ID | GeneID 490 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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