Anti-ATG16L

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG55141.100 100 µl - -

6 - 14 business days*

624.00€
 
Protein function: Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the... more
Product information "Anti-ATG16L"
Protein function: Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane (PubMed:24553140, PubMed:23376921, PubMed:24954904, PubMed:27273576, PubMed:23392225). Regulates mitochondrial antiviral signaling (MAVS)-dependent type I interferon (IFN-I) production (PubMed:25645662). Negatively regulates NOD1- and NOD2- driven inflammatory cytokine response (PubMed:24238340). Instead, promotes with NOD2 an autophagy-dependent antibacterial pathway (PubMed:20637199). Plays a role in regulating morphology and function of Paneth cell (PubMed:18849966). [The UniProt Consortium]
Keywords: Anti-APG16L, Anti-ATG16L1, Anti-APG16-like 1, Anti-Autophagy-related protein 16-1
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG55141

Properties

Application: ICC, IF, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: KLH-conjugated synthetic peptide from Human ATG16L
Format: Ammonium Sulfate Precipitated

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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