Anti-ATF7IP

Anti-ATF7IP
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-CAB10446.50 50 µl - -

9 - 20 business days*

352.00€
G-CAB10446.100 100 µl -

9 - 20 business days*

448.00€
 
IHC 1:50 - 1:200. Protein function: Recruiter that couples transcriptional factors to general... more
Product information "Anti-ATF7IP"
IHC 1:50 - 1:200. Protein function: Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Required for HUSH-mediated heterochromatin formation and gene silencing (PubMed:27732843). Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1 (PubMed:12665582). Stabilizes SETDB1, is required to stimulate histone methyltransferase activity of SETDB1 and facilitates the conversion of dimethylated to trimethylated H3 'Lys-9' (H3K9me3). The complex formed with MBD1 and SETDB1 represses transcription and couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) (PubMed:14536086, PubMed:27732843). Facilitates telomerase TERT and TERC gene expression by SP1 in cancer cells (PubMed:19106100). [The UniProt Consortium]
Keywords: Anti-hAM, Anti-MCAF, Anti-P621, Anti-ATF-IP, Anti-ATF-interacting protein, Anti-ATF7-interacting protein, Anti-ATFa-associated modulator, Anti-MBD1-containing chromatin-associated factor 1, Anti-Activating transcription factor 7-interacting protein 1, ATF
Supplier: Assay Genie
Supplier-Nr: CAB10446

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human

Database Information

UniProt ID : Q6VMQ6 | Matching products
Gene ID GeneID 55729 | Matching products

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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