Anti-Ataxin 1 / ATXN1, clone 2B13G8

Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-RQ7132 100 µg - -

3 - 10 business days*

755.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Ataxin-1 is a protein that in humans is... more
Product information "Anti-Ataxin 1 / ATXN1, clone 2B13G8"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Ataxin-1 is a protein that in humans is encoded by the ATXN1 gene. It is a causative factor for spinocerebellar ataxia type 1 (SCA1), and the related Brother of ATXN1 (BOAT1), are human proteins involved in transcriptional repression. ATXN1 and BOAT1 might participate in several Notch-controlled developmental and pathological processes. Protein function: Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ- mediated repression. Binds RNA in vitro. May be involved in RNA metabolism (PubMed:21475249). In concert with CIC and ATXN1L, involved in brain development. [The UniProt Consortium]
Keywords: Anti-ATX1, Anti-ATXN1, Anti-Ataxin-1, Anti-Spinocerebellar ataxia type 1 protein, Ataxin 1 Antibody / ATXN1
Supplier: NSJ Bioreagents
Supplier-Nr: RQ7132

Properties

Application: WB, IHC (paraffin), FC
Antibody Type: Monoclonal
Clone: 2B13G8
Conjugate: No
Host: Mouse
Species reactivity: human, mouse, rat
Immunogen: C-terminal amino acids ESRKLEKSEDEPPLTLPKPSLIPQEVKICIE
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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