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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-11-8069-25 | 25 µg | - |
3 - 11 business days* |
134.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
ASAP (Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1) or Development and... more
Product information "Anti-ASAP1"
ASAP (Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1) or Development and differentiation-enhancing factor 1 or DDEF1 is an ADP-ribosylation factor (ARF) GTPase-activating protein with two known isoforms: ASAP1a and ASAP1b (125 and 126 kDa, respectively). ASAP contains a pleckstrin homology (PH) domain, a zinc finger motif, 3 ankyrin repeats, a proline-rich region containing several SH3 ligand motifs, and an SH3 domain. GTPase-activating property of ASAP1 is induced by phosphatidylinositol 4,5-biphosphate (PIP2) of the PH domain. ASAP1 plays an important role in cytoskeleton remodeling and regulation of membrane trafficking. ASAP1 acts as a proto-oncogene in breast cancer and other malignant tumors. ASAP is highly expressed in brain tissue. Protein function: Possesses phosphatidylinositol 4,5-bisphosphate- dependent GTPase-activating protein activity for ARF1 (ADP ribosylation factor 1) and ARF5 and a lesser activity towards ARF6. May coordinate membrane trafficking with cell growth or actin cytoskeleton remodeling by binding to both SRC and PIP2. May function as a signal transduction protein involved in the differentiation of fibroblasts into adipocytes and possibly other cell types. Plays a role in ciliogenesis. [The UniProt Consortium]
Keywords: | Anti-DDEF1, Anti-ASAP1, Anti-DEF-1, Anti-PIP2-dependent ARF1 GAP, Anti-ARF GTPase-activating protein 1, Anti-Differentiation-enhancing factor 1, Anti-Development and differentiation-enhancing factor 1, Polyclonal Antibody to ASAP1 |
Supplier: | Abeomics |
Supplier-Nr: | 11-8069-25 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | A partial length recombinant ASAP1 protein (amino acids 912-1115) was used as the immunogen for this antibody. |
Format: | Purified |
Database Information
KEGG ID : | K12488 | Matching products |
UniProt ID : | Q9ULH1 | Matching products |
Gene ID | GeneID 50807 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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