Anti-ARPC2

Anti-ARPC2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES19103.50 50 µl - -

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169.00€
ELK-ES19103.100 100 µl - -

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283.00€
 
Protein function: Actin-binding component of the Arp2/3 complex, a multiprotein complex that... more
Product information "Anti-ARPC2"
Protein function: Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079). Seems to contact the mother actin filament (PubMed:9230079). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (PubMed:29925947). [The UniProt Consortium] Recommended dilutions: WB 1:1000-2000. Cellular localization: Cytoplasm, cytoskeleton . Cell projection . Cell junction, synapse, synaptosome . Nucleus .
Keywords: Anti-ARC34, Anti-ARPC2, Anti-p34-ARC, Anti-PRO2446, Anti-Arp2/3 complex 34 kDa subunit, Anti-Actin-related protein 2/3 complex subunit 2, ARPC2 rabbit pAb
Supplier: ELK Biotechnology
Supplier-Nr: ES19103

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Synthesized peptide derived from human ARPC2 AA range: 147-197
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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