Anti-ARPC1B

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA004832.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA004832.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Component of the Arp2/3 complex, a multiprotein complex that mediates actin... more

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Product information "Anti-ARPC1B"

Protein function: Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:11741539, PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:11741539, PubMed:9230079). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double- strand breaks (DSBs) (PubMed:29925947). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 94% and to rat: 94%

Keywords:	Anti-ARC41, Anti-p41-ARC, Anti-Arp2/3 complex 41 kDa subunit, Anti-Actin-related protein 2/3 complex subunit 1B
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA004832

Properties

Application:	IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: TVCLADADKK MAVATLASET LPLLALTFIT DNSLVAAGHD CFPVLFTYDA AAGMLSFGGR LDVPKQSSQR GLTARERFQN LDKKASSEGG TAAGAGLDSL HKNSVSQISV LSGGKAKCSQ FCTTGMDGGM SIWDVKSLES A (ATA-APrEST86831)