Anti-ARHGEF5 (IHC)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
IHC-00652-T	10 µl (2500 ng)		-		2 - 8 business days*		164.00€
IHC-00652	100 µl (25 µg)		-		2 - 8 business days*		623.00€

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Protein function: Guanine nucleotide exchange factor which activates Rho GTPases... more

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Product information "Anti-ARHGEF5 (IHC)"

Protein function: Guanine nucleotide exchange factor which activates Rho GTPases (PubMed:15601624). Strongly activates RHOA (PubMed:15601624). Also strongly activates RHOB, weakly activates RHOC and RHOG and shows no effect on RHOD, RHOV, RHOQ or RAC1. Involved in regulation of cell shape and actin cytoskeletal organization (PubMed:15601624). Plays a role in actin organization by generating a loss of actin stress fibers and the formation of membrane ruffles and filopodia (PubMed:14662653). Required for SRC-induced podosome formation. Involved in positive regulation of immature dendritic cell migration. [The UniProt Consortium]

Keywords:	Anti-TIM, Anti-ARHGEF5, Anti-p60 TIM, Anti-Ephexin-3, Anti-Oncogene TIM, Anti-Rho guanine nucleotide exchange factor 5, Anti-Guanine nucleotide regulatory protein TIM, Anti-Transforming immortalized mammary oncogene
Supplier:	Bethyl Laboratories
Supplier-Nr:	IHC-00652

Properties

Application:	IHC, IHC-IF
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: chimpanzee, white-tufted-ear marmoset)
Immunogen:	The epitope recognized by IHC-00652 maps to a region between residue 600 and 650 of human Rho guanine nucleotide exchange factor (GEF) 5 using the numbering given in entry NP_005426.2 (GeneID 7984).
Format:	Antigen Affinity Purified