Anti-ARHGEF1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA060784.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA060784.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Seems to play a role in the regulation of RhoA GTPase by guanine... more

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Product information "Anti-ARHGEF1"

Protein function: Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13) subunits (PubMed:9641915, PubMed:9641916). Acts as GTPase-activating protein (GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor (GEF) for RhoA GTPase (PubMed:9641915, PubMed:9641916, PubMed:8810315, PubMed:30521495). Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain (PubMed:9641916). This GEF activity is inhibited by binding to activated GNA12 (PubMed:9641916). Mediates angiotensin-2-induced RhoA activation (PubMed:20098430). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 86% and to rat: 87%

Keywords:	Anti-Sub1.5, Anti-ARHGEF1, Anti-p115RhoGEF, Anti-p115-RhoGEF, Anti-Rho guanine nucleotide exchange factor 1, Anti-115 kDa guanine nucleotide exchange factor
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA060784

Properties

Application:	WB, ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: LRVPVPPNVA FELDRTRADL ISEDVQRRFV QEVVQSQQVA VGRQLEDFRS KRLMGMTPWE QELAQLEAWV GRDRASYEAR ERHVAERLLM HLEEMQHTIS TDEEKSAAVV NAIGL (ATA-APrEST89910)