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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ARG57110.50 | 50 µl | - | - |
6 - 14 business days* |
488.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: GTP-binding protein that functions as an allosteric activator of the cholera... more
Product information "Anti-ARF1, clone 1B3"
Protein function: GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. The GTP-bound form interacts with PICK1 to limit PICK1-mediated inhibition of Arp2/3 complex activity, the function is linked to AMPA receptor (AMPAR) trafficking, regulation of synaptic plasicity of excitatory synapses and spine shrinkage during long-term depression (LTD). [The UniProt Consortium]
Keywords: | Anti-ARF1, Anti-ADP-ribosylation factor 1 |
Supplier: | Arigo Biolaboratories |
Supplier-Nr: | ARG57110 |
Properties
Application: | WB, FC, ICC, IF |
Antibody Type: | Monoclonal |
Clone: | 1B3 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Recombinant fragment around aa. 1-181 of Human ARF1 |
Format: | Purified |
Database Information
KEGG ID : | K07937 | Matching products |
UniProt ID : | P84077 | Matching products |
Gene ID | GeneID 375 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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