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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES6753.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES6753.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The protein encoded by this gene is a GTPase-activating protein, which associates with the Golgi... more
Product information "Anti-ARF GAP1"
The protein encoded by this gene is a GTPase-activating protein, which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013], Protein function: GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle's fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine. [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.. Cellular localization: Cytoplasm . Golgi apparatus . Associates with the Golgi complex. .
Keywords: | Anti-ARFGAP1, Anti-ARF1GAP, Anti-ARF1 GAP, Anti-ARF GAP 1, Anti-ARF1-directed GTPase-activating protein, Anti-ADP-ribosylation factor 1 GTPase-activating protein, Anti-ADP-ribosylation factor GTPase-activating protein 1, ARF GAP1 rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES6753 |
Properties
Application: | WB, IHC, IF, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat, monkey, bovine |
Immunogen: | The antiserum was produced against synthesized peptide derived from human ARFGAP1. AA range:171-220 |
MW: | 48 kD |
Format: | Antiserum |
Database Information
KEGG ID : | K12492 | Matching products |
UniProt ID : | Q8N6T3 | Matching products |
Gene ID | GeneID 55738 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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