Anti-ARF-BP1

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG56849.50 50 µg - -

6 - 14 business days*

520.00€
 
Protein function: E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent... more
Product information "Anti-ARF-BP1"
Protein function: E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Regulates apoptosis by catalyzing the polyubiquitination and degradation of MCL1. Mediates monoubiquitination of DNA polymerase beta (POLB) at 'Lys-41', 'Lys-61' and 'Lys-81', thereby playing a role in base-excision repair. Also ubiquitinates the p53/TP53 tumor suppressor and core histones including H1, H2A, H2B, H3 and H4. Binds to an upstream initiator-like sequence in the preprodynorphin gene. Regulates neural differentiation and proliferation by catalyzing the polyubiquitination and degradation of MYCN. May regulate abundance of CDC6 after DNA damage by polyubiquitinating and targeting CDC6 to degradation. Mediates polyubiquitination of isoform 2 of PA2G4. [The UniProt Consortium]
Keywords: Anti-Mule, Anti-LASU1, Anti-HUWE1, Anti-HectH9, Anti-URE-B1, Anti-ARF-BP1, Anti-HSPC272, Anti-KIAA0312, EC=2.3.2.26, Anti-ARF-binding protein 1, Anti-URE-binding protein 1, Anti-Large structure of UREB1, Anti-Mcl-1 ubiquitin ligase E3
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG56849

Properties

Application: WB, ICC, IF
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: mouse, rat)
Immunogen: Synthetic peptide around 19 aa (C-terminus) of Human ARF-BP1
Format: Antigen Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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