Anti-ARF-BP1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
600-401-C03	100 µg		-	-	6 - 10 business days*		684.00€

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Protein function: E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent... more

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Product information "Anti-ARF-BP1"

Protein function: E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Regulates apoptosis by catalyzing the polyubiquitination and degradation of MCL1. Mediates monoubiquitination of DNA polymerase beta (POLB) at 'Lys-41', 'Lys-61' and 'Lys-81', thereby playing a role in base-excision repair. Also ubiquitinates the p53/TP53 tumor suppressor and core histones including H1, H2A, H2B, H3 and H4. Binds to an upstream initiator-like sequence in the preprodynorphin gene. Regulates neural differentiation and proliferation by catalyzing the polyubiquitination and degradation of MYCN. May regulate abundance of CDC6 after DNA damage by polyubiquitinating and targeting CDC6 to degradation. [The UniProt Consortium]

Keywords:	Anti-Mule, Anti-HUWE1, Anti-LASU1, Anti-HectH9, Anti-URE-B1, Anti-ARF-BP1, Anti-HSPC272, Anti-KIAA0312, EC=6.3.2.-, Anti-ARF-binding protein 1, Anti-URE-binding protein 1, Anti-Large structure of UREB1, Anti-Mcl-1 ubiquitin ligase E3
Supplier:	Rockland Immunochemicals
Supplier-Nr:	600-401-C03

Properties

Application:	ELISA, IFM, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	synthetic peptide corresponding to a region near the C-terminus of human ARF-BP1 protein
Format:	Purified