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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-30-1358-0.1 | 100 µg | - |
3 - 11 business days* |
653.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
ARAP1 (angiotensin II type 1 receptor-associated protein) is an adaptor protein with ArfGAP and... more
Product information "Anti-ARAP1 / centaurin Monoclonal Antibody (Clone:ARAP1-2)"
ARAP1 (angiotensin II type 1 receptor-associated protein) is an adaptor protein with ArfGAP and RhoGAP activities, containing five PH domains and ankyrin repeate. This adaptor seems to serve as a link between phosphoinositide- Arf-, and Rho-mediated cell signaling. ARAP1 supports the plasma membrane recycling of angiotensin II type 1 receptor (AT1) and is important also for cell-specific trafficking of pro-death receptor TRAIL-R1 (DR4) to the plasma membrane, thus promoting the TRAIL-induced apoptosis in certain cell types. ARAP1 also affects cell spreading. Protein function: Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Has a preference for ARF1 and ARF5. [The UniProt Consortium]
Keywords: | Anti-ARAP1, Anti-Cnt-d2, Anti-CENTD2, Anti-Centaurin-delta-2, Anti-Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1, Anti-ARAP1 / centaurin Monoclonal Antibody (Clone:ARAP1-2) |
Supplier: | Abeomics |
Supplier-Nr: | 30-1358 |
Properties
Application: | IP, WB, ICC |
Antibody Type: | Monoclonal |
Clone: | ARAP1-2 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | His6-tagged protein corresponding to amino acids 1190-1450 of human ARAP1 |
Format: | Affinity Purified |
Database Information
KEGG ID : | K18439 | Matching products |
UniProt ID : | Q96P48 | Matching products |
Gene ID | GeneID 116985 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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You will get a certificate here
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