Anti-Aquaporin 5

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Aquaporin 5, also known as AQP5, is a water channel protein. The aquaporins(AQPs) are a family of more than 10 homologous water transporting proteins expressed in many mammalian epithelia and endothelia. AQP5 is expressed in corneal and lacrimal gland epithelia. Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. Protein function: Forms a water-specific channel. Plays an important role in fluid secretion in salivary glands (PubMed:10400615, PubMed:16571723, PubMed:18027168). Required for TRPV4 activation by hypotonicity. Together with TRPV4, controls regulatory volume decrease in salivary epithelial cells (PubMed:16571723). Seems to play a redundant role in water transport in the eye, lung and in sweat glands (PubMed:10619865, PubMed:12042359, PubMed:18027168). [The UniProt Consortium]