Anti-AQR

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA040624.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA040624.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11991638,... more

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Product information "Anti-AQR"

Protein function: Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11991638, PubMed:25599396, PubMed:28502770, PubMed:28076346). Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis (PubMed:16949364). Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly (PubMed:16949364). May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing (PubMed:16949364). Has ATP-dependent RNA helicase activity and can unwind double-stranded RNA molecules with a 3' overhang (in vitro) (PubMed:25599396). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 98% and to rat: 98%

Keywords:	Anti-AQR, Anti-IBP160, Anti-KIAA0560, Anti-RNA helicase aquarius, Anti-Intron-binding protein of 160 kDa
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA040624

Properties

Application:	ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: SEPVTMDKVH YCERFIELMI DLEALLPTRR WFNTILDDSH LLVHCYLSNL VRREEDGHLF SQLLDMLKFY TGFEINDQTG NALTENEMTT IHYDRITSLQ RAAFAHFPEL YDFALSNVAE V (ATA-APrEST90916)