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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-R30177 | 100 µg | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Many growth factors and cytokines act as... more
Product information "Anti-Apoptosis inhibitor 5"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Many growth factors and cytokines act as cellular survival factors by preventing programmed cell death(apoptosis). Apoptosis inhibitor 5 (API5) is an antiapoptotic factor which may have a role in protein assembly. The API5 gene to chromosome 11p12 based on an alignment of the API5 sequence with the genomic sequence It is a critical determinant of E2F1-induced apoptosis, acting downstream of E2F to suppress E2F-dependent apoptosis without generally blocking E2F-dependent transcription. Protein function: Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. [The UniProt Consortium]
Keywords: | Anti-FIF, Anti-MIG8, Anti-API-5, Anti-AAC-11, Anti-Protein XAGL, Anti-Apoptosis inhibitor 5, Anti-Antiapoptosis clone 11 protein, Anti-Cell migration-inducing gene 8 protein, Anti-Fibroblast growth factor 2-interacting factor, Apoptosis inhibitor 5 Antibo |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | R30177 |
Properties
Application: | WB, IHC (paraffin), (IF), IF |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | An amino acid sequence from the C-terminus of human Apoptosis inhibitor 5 (amino acids 487-504 of isoform b, KYSSNLGNFNYERSLQGK) |
Format: | Purified |
Database Information
UniProt ID : | Q9BZZ5 | Matching products |
Gene ID | GeneID 8539 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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