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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES1678.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES1678.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after... more
Product information "Anti-API5"
This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011], Protein function: Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.. Cellular localization: Nucleus . Cytoplasm . Mainly nuclear. Can also be cytoplasmic., [Isoform 3]: Cytoplasm.
Keywords: | Anti-FIF, Anti-MIG8, Anti-API-5, Anti-AAC-11, Anti-Protein XAGL, Anti-Apoptosis inhibitor 5, Anti-Antiapoptosis clone 11 protein, Anti-Cell migration-inducing gene 8 protein, Anti-Fibroblast growth factor 2-interacting factor, API5 rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES1678 |
Properties
Application: | WB, IHC, IF, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse |
Immunogen: | The antiserum was produced against synthesized peptide derived from human API-5. AA range:421-470 |
MW: | 58 kD |
Format: | Antiserum |
Database Information
UniProt ID : | Q9BZZ5 | Matching products |
Gene ID | GeneID 8539 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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