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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the... more
Product information "Anti-APEH"
This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma. Protein function: This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N- acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser. [The UniProt Consortium]
Keywords: | Anti-APH, Anti-OPH, Anti-APEH, Anti-AARE, Anti-D3F15S2, EC=3.4.19.1, Anti-Acyl-peptide hydrolase, Anti-Acylaminoacyl-peptidase, Anti-Oxidized protein hydrolase, Anti-Acylamino-acid-releasing enzyme, APEH Polyclonal Antibody |
Supplier: | Elabscience |
Supplier-Nr: | E-AB-64657 |
Properties
Application: | WB, IF |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Recombinant protein of human APEH |
Database Information
KEGG ID : | K01303 | Matching products |
UniProt ID : | P13798 | Matching products |
Gene ID | GeneID 327 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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