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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
BOT-BNUB0882-100 | 100 µl | - |
Request delivery time estimate |
321.00€
|
|||
BOT-BNUB0882-500 | 500 µl | - |
Request delivery time estimate |
693.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
This antibody recognizes a protein of 110 kDa, which is identified as androgen receptor (AR). It... more
Product information "Anti-Androgen Receptor(DHTR/882), 0.2mg/mL"
This antibody recognizes a protein of 110 kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. AR functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. The expression of AR is reportedly inversely correlated with histologic grade, ie, well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin.This MAb is superb for staining of formalin/paraffin tissues. Primary antibodies are available purified, or with a selection of fluorescent CF(R) Dyes and other labels. CF(R) Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF(R)405S and CF(R)405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors. Concentration: 0.2 mg/mL Storage buffer: PBS, 0.05% BSA, 0.05% azide
Keywords: | Androgen Receptor(DHTR/882), 0.2mg/mL, |
Supplier: | Biotium |
Supplier-Nr: | BNUB0882 |
Properties
Application: | IHC (paraffin) (verif.) |
Conjugate: | No |
Format: | Purified, With BSA |
Database Information
Handling & Safety
Storage: | +20°C |
Shipping: | +20°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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