Anti-ALKBH7

Anti-ALKBH7
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG57318.100 100 µl - -

6 - 14 business days*

624.00€
 
Protein function: May function as protein hydroxylase, can catalyze auto- hydroxylation at... more
Product information "Anti-ALKBH7"
Protein function: May function as protein hydroxylase, can catalyze auto- hydroxylation at Leu-110 (in vitro), but this activity may be due to the absence of the true substrate (PubMed:25122757). Required to induce programmed necrosis in response to DNA damage caused by cytotoxic alkylating agents. Acts by triggering the collapse of mitochondrial membrane potential and loss of mitochondrial function that leads to energy depletion and cell death (PubMed:23666923). ALKBH7-mediated necrosis is probably required to prevent the accumulation of cells with DNA damage (PubMed:23666923). Does not display DNA demethylase activity (PubMed:23666923). Involved in fatty acid metabolism. [The UniProt Consortium]
Keywords: Anti-ABH7, Anti-ALKBH7, EC=1.14.11.-, Anti-Spermatogenesis-associated protein 11, Anti-Alkylated DNA repair protein alkB homolog 7, Anti-Spermatogenesis cell proliferation-related protein, Anti-Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG57318

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: mouse
Immunogen: Recombinant Protein of Human ALKBH7
MW: 25 kD
Format: Antigen Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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