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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ELK-ES19433.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
| ELK-ES19433.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Catalyzes the methylation of 5-carboxymethyl uridine to 5- methylcarboxymethyl... more
Product information "Anti-ALKB8"
Protein function: Catalyzes the methylation of 5-carboxymethyl uridine to 5- methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its methyltransferase domain (PubMed:20123966, PubMed:20308323, PubMed:31079898). Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA (PubMed:20123966, PubMed:20308323). Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys)(PubMed:20308323). Binds tRNA and catalyzes the iron and alpha-ketoglutarate dependent hydroxylation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its dioxygenase domain, giving rise to 5-(S)- methoxycarbonylhydroxymethyluridine, has a preference for tRNA(Gly) (PubMed:21285950). Required for normal survival after DNA damage (PubMed:20308323). May inhibit apoptosis and promote cell survival and angiogenesis (PubMed:19293182). [The UniProt Consortium] Recommended dilutions: WB 1:1000-2000. Cellular localization: Cytoplasm . Nucleus . Predominantly cytoplasmic. .
| Keywords: | Anti-ABH8, Anti-ALKBH8, Anti-Alkylated DNA repair protein alkB homolog 8, Anti-Probable alpha-ketoglutarate-dependent dioxygenase ABH8, Anti-tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8, ALKB8 rabbit pAb |
| Supplier: | ELK Biotechnology |
| Supplier-Nr: | ES19433 |
Properties
| Application: | WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
| Immunogen: | Synthesized peptide derived from human ALKB8 AA range: 27-77 |
| Format: | Purified |
Database Information
| KEGG ID : | K10770 | Matching products |
| UniProt ID : | Q96BT7 | Matching products |
| Gene ID | GeneID 91801 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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