Anti-ALKB7

Anti-ALKB7
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES9269.50 50 µl - -

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169.00€
ELK-ES9269.100 100 µl - -

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283.00€
 
similarity:Belongs to the alkB family., Protein function: May function as protein hydroxylase,... more
Product information "Anti-ALKB7"
similarity:Belongs to the alkB family., Protein function: May function as protein hydroxylase, can catalyze auto- hydroxylation at Leu-110 (in vitro), but this activity may be due to the absence of the true substrate (PubMed:25122757). Required to induce programmed necrosis in response to DNA damage caused by cytotoxic alkylating agents. Acts by triggering the collapse of mitochondrial membrane potential and loss of mitochondrial function that leads to energy depletion and cell death (PubMed:23666923). ALKBH7-mediated necrosis is probably required to prevent the accumulation of cells with DNA damage (PubMed:23666923). Does not display DNA demethylase activity (PubMed:23666923). Involved in fatty acid metabolism. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000. Cellular localization: Mitochondrion matrix .
Keywords: Anti-ABH7, Anti-ALKBH7, EC=1.14.11.-, Anti-Spermatogenesis-associated protein 11, Anti-Alkylated DNA repair protein alkB homolog 7, Anti-Spermatogenesis cell proliferation-related protein, Anti-Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, ALK
Supplier: ELK Biotechnology
Supplier-Nr: ES9269

Properties

Application: WB, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: Synthesized peptide derived from human protein . at AA range: 10-90
MW: 24 kD
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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