Anti-AKIR1, CT (AKIRIN1, C1orf108, Akirin-1) (Azide free) (FITC)

Anti-AKIR1, CT (AKIRIN1, C1orf108, Akirin-1) (Azide free) (FITC)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
031737-FITC.200 200 µl - -

3 - 19 business days*

790.00€
 
The highly conserved, nuclear-localized AKIRIN1 and Akirin2 proteins critically regulate the... more
Product information "Anti-AKIR1, CT (AKIRIN1, C1orf108, Akirin-1) (Azide free) (FITC)"
The highly conserved, nuclear-localized AKIRIN1 and Akirin2 proteins critically regulate the transcription of NF-kB dependent genes and are required for defense against Gram-negative bacteria in the immune deficiency and NF-kB pathways. AKIRIN1 is dispensable in the mouse, and neither knockout mice nor cells derived from them have obvious distinctive phenotypes. In contrast, Akirin2 is required for development in the mouse and knockout of both Akirin homologs in mice show that Akirin2 is required downstream of toll-like receptor (TLR), TNF-alpha and IL-1beta signaling, and for the production of IL-6. Akirin2 is functionally closer to the single gene in Drosophila, as the homozygous null D. melanogaster Akirin mutants show a similar, mid-to-early embryonic death. Applications: Suitable for use in Western Blot, FLISA, Recommended Dilution: FLISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Keywords: Anti-AKIRIN1, Anti-C1orf108, Anti-Akirin-1
Supplier: United States Biological
Supplier-Nr: 031737-FITC

Properties

Application: FLISA, WB
Antibody Type: Polyclonal
Conjugate: FITC
Host: Rabbit
Reactivity: Human
Immunogen: AKIR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-158 amino acids from the C-terminal region of human AKIR1.
Format: Affinity Purified

Database Information

UniProt ID : Q9H9L7 | Matching products
Gene ID : GeneID 79647 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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