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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A301-366A-T | 10 µl (2 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A301-366A | 100 µl | - |
2 - 8 business days* |
588.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Could play a role in constitutive transport element (CTE)-mediated gene... more
Product information "Anti-AKAP8L/HA95"
Protein function: Could play a role in constitutive transport element (CTE)-mediated gene expression by association with DHX9. Increases CTE-dependent nuclear unspliced mRNA export (PubMed:10748171, PubMed:11402034). Proposed to target PRKACA to the nucleus but does not seem to be implicated in the binding of regulatory subunit II of PKA (PubMed:10761695, PubMed:11884601). May be involved in nuclear envelope breakdown and chromatin condensation. May be involved in anchoring nuclear membranes to chromatin in interphase and in releasing membranes from chromating at mitosis (PubMed:11034899). May regulate the initiation phase of DNA replication when associated with TMPO isoform Beta (PubMed:12538639). Required for cell cycle G2/M transition and histone deacetylation during mitosis. In mitotic cells recruits HDAC3 to the vicinity of chromatin leading to deacetylation and subsequent phosphorylation at 'Ser-10' of histone H3, in this function seems to act redundantly with AKAP8 (PubMed:16980585). May be involved in regulation of pre-mRNA splicing (PubMed:17594903). [The UniProt Consortium]
Keywords: | Anti-HA95, Anti-HAP95, Anti-NAKAP, Anti-AKAP8L, Anti-HRIHFB2018, Anti-Neighbor of AKAP95, Anti-AKAP8-like protein, Anti-Homologous to AKAP95 protein, Anti-Helicase A-binding protein 95, Anti-A-kinase anchor protein 8-like |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A301-366A |
Properties
Application: | WB, IP, IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human (Expected: gorilla, chimpanzee, chinese hamster, naked mole rat, northern white-cheeked gibbon) |
Immunogen: | synthetic peptide. The epitope recognized by A301-366A-T maps to a region between residue 596 and 646 of human A kinase (PRKA) anchor protein 8-like (helicase A-binding protein 95 kDa) using the numbering given in entry NP_055186.2 (GeneID 26993). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K15978 | Matching products |
UniProt ID : | Q9ULX6 | Matching products |
Gene ID | GeneID 26993 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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