Anti-AID (Activation induced cytidine deaminase)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
BR-G01066.100	100 µl		-		Request delivery time estimate		627.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Single-stranded DNA-specific cytidine deaminase. Involved in somatic... more

Close menu

Product information "Anti-AID (Activation induced cytidine deaminase)"

Protein function: Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation (SHM), gene conversion, and class-switch recombination (CSR) in B-lymphocytes by deaminating C to U during transcription of Ig-variable (V) and Ig-switch (S) region DNA. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses (PubMed:18722174, PubMed:21385873, PubMed:21518874, PubMed:27716525). May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation (PubMed:21496894). [The UniProt Consortium]

Keywords:	Anti-AID, Anti-AICDA, Anti-Cytidine aminohydrolase, Anti-Activation-induced cytidine deaminase, Anti-Single-stranded DNA cytosine deaminase
Supplier:	Bertin Bioreagent
Supplier-Nr:	G01066

Properties

Application:	ELISA, WB, IF, IP
Antibody Type:	Monoclonal
Clone:	2E11
Conjugate:	No
Host:	Mouse
Species reactivity:	mouse, human
Immunogen:	Synthetic peptide coupled to Ovalbumin.