Anti-AGRP

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA041017.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA041017.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Plays a role in weight homeostasis. Involved in the control of feeding behavior... more

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Product information "Anti-AGRP"

Protein function: Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin system. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R. Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity. It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 86% and to rat: 79%

Keywords:	Anti-AGRT, Anti-AGRP, Anti-Agouti-related protein
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA041017

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: PLKKTTAEQA EEDLLQEAQA LAEVLDLQDR EPRSSRRCVR LHESCLGQQV PCCDPCATCY CRFFNAFCYC RKLGTAM (ATA-APrEST82235)