Anti-AFX (Ab-197)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABE-35-1505-100	100 µg		-		3 - 11 business days*		682.00€

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Transcription factor involved in the regulation of the insulin signaling pathway. Binds to... more

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Product information "Anti-AFX (Ab-197)"

Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Protein function: Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity. [The UniProt Consortium]

Keywords:	Anti-AFX, Anti-FOXO4, Anti-Forkhead box protein O4, Anti-Fork head domain transcription factor AFX1, Polyclonal Antibody to AFX (Ab-197)
Supplier:	Abeomics
Supplier-Nr:	35-1505

Properties

Application:	WB, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Peptide sequence around aa. 195~199 (A-A-S-M-D) derived from Human AFX.
Format:	Purified