Anti-AFG3L2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG55137.100	100 µl		-	-	6 - 14 business days*		624.00€

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Protein function: ATP-dependent protease which is essential for axonal and neuron development. In... more

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Product information "Anti-AFG3L2"

Protein function: ATP-dependent protease which is essential for axonal and neuron development. In neurons, mediates degradation of SMDT1/EMRE before its assembly with the uniporter complex, limiting the availability of SMDT1/EMRE for MCU assembly and promoting efficient assembly of gatekeeper subunits with MCU (PubMed:27642048). Required for the maturation of paraplegin (SPG7) after its cleavage by mitochondrial-processing peptidase (MPP), converting it into a proteolytically active mature form. [The UniProt Consortium]

Keywords:	Anti-AFG3L2, Anti-AFG3-like protein 2, Anti-Paraplegin-like protein
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG55137

Properties

Application:	IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: mouse, bovine)
Immunogen:	KLH-conjugated synthetic peptide corresponding to aa. 52-80 (N-terminus) of Human AFG3L2
Format:	Purified